Mouse Biology Program Content / Mouse Biology Program Content for ºÙºÙÊÓƵ en NIH Renews Knockout Mouse Project for 3rd Time /health/news/nih-renews-knockout-mouse-project-3rd-time <p><span><span><span><span><span><span><span><span><span><span><span><span><span>The University of California, Davis, has been awarded just over $12 million from the National Institutes of Health under the third and final five-year phase of the Knockout Mouse Phenotyping Project, or KOMP2. ºÙºÙÊÓƵ is the lead organization in a consortium involving a partnership with The Centre for Phenogenomics in Toronto. </span></span></span></span></span></span></span></span></span></span></span></span></span></p> August 15, 2022 - 10:00am Andy Fell /health/news/nih-renews-knockout-mouse-project-3rd-time Grant to Create Humanized Mice for HIV Studies /blog/grant-create-humanized-mice-hiv-studies <p><span><span><span><span><span><span><span><span>Creating a new type of ‘humanized mouse’ that can be infected with HIV is the goal of new project at the <a href="https://mbp.mousebiology.org">Mouse Biology Program</a> of the University of California, Davis. The work is funded with a grant of nearly $500,000 from the National Institutes of Health. </span></span></span></span></span></span></span></span></p> August 12, 2022 - 2:41pm Andy Fell /blog/grant-create-humanized-mice-hiv-studies A Map of Mouse Brain Metabolism in Aging /blog/map-mouse-brain-metabolism-aging <p>The first atlas of metabolites in the mouse brain has been published by a team led by ºÙºÙÊÓƵ researchers. The dataset includes 1,547 different molecules across 10 brain regions in male and female laboratory mice from adolescence through adulthood and into advanced old age. The work is published Oct. 15 in the&nbsp;<a href="https://www.nature.com/articles/s41467-021-26310-y">Nature Communications</a>. The complete dataset is publicly available at&nbsp;<a href="https://mouse.atlas.metabolomics.us/">https://mouse.atlas.metabolomics.us/</a>.</p> October 15, 2021 - 4:09pm Andy Fell /blog/map-mouse-brain-metabolism-aging NIH Grant to Create Humanized Mice Susceptible to COVID-19 /news/nih-grant-create-humanized-mice-susceptible-covid-19 <p>The National Institutes of Health has awarded a grant of $1.2 million to the Mouse Biology Program at the University of California, Davis, to create mice that are susceptible to the COVID-19 virus, and to distribute them to researchers.</p> <p>The goal is to create mice that can be used to reproduce human COVID-19 disease, said Kent Lloyd, director of the Mouse Biology Program and professor in the Department of Surgery at the ºÙºÙÊÓƵ School of Medicine.</p> August 03, 2020 - 1:36pm Andy Fell /news/nih-grant-create-humanized-mice-susceptible-covid-19 COVID-19 Vaccine With Patch Delivery Technology Enters Preclinical Testing at ºÙºÙÊÓƵ /coronavirus/news/covid-19-vaccine-patch-delivery-technology-enters-preclinical-testing-uc-davis <p><a href="https://www.verndariinc.com">Verndari Inc.</a>, a&nbsp;biopharmaceutical company, announced today (April 29) that it will begin preclinical testing this week at the University of California, Davis, Mouse Biology Program to evaluate a potential vaccine and delivery system for COVID-19.</p> April 29, 2020 - 4:49pm Andy Fell /coronavirus/news/covid-19-vaccine-patch-delivery-technology-enters-preclinical-testing-uc-davis Mouse Genome Studies Show Disease Models and Sex Differences /news/mouse-genome-studies-show-disease-models-and-sex-differences <p>Two major studies by international teams published today (June 26) show the value and potential of genetically modified mice in biomedical research — and also the pitfalls of conducting research with subjects of only one sex. Researchers at the ºÙºÙÊÓƵ Mouse Biology Program collaborated on both studies, published in the journals Nature Genetics and Nature Communications.&nbsp;&nbsp;</p> June 26, 2017 - 3:48pm Andy Fell /news/mouse-genome-studies-show-disease-models-and-sex-differences