Pharmacology Content / Pharmacology Content for ºÙºÙÊÓƵ en Revealing a Key Process in How the Brain Forms Memories /news/revealing-key-process-how-brain-forms-memories <p>The process by which memories are formed in the hippocampus region of the brain is complex. It relies on a precise choreography of interactions between neurons, neurotransmitters, receptors and enzymes.</p> March 29, 2023 - 2:00pm Andy Fell /news/revealing-key-process-how-brain-forms-memories Anti-inflammation Drug Combination May Help Pancreatic and Liver Cancer Patients /blog/anti-inflammation-drug-combination-may-help-pancreatic-and-liver-cancer-patients <p>A drug candidate discovered and developed decades ago in the laboratory of ºÙºÙÊÓƵ distinguished professor Bruce Hammock may help control the body’s raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients.</p> <p>The research team, based in the laboratories of Dipak Panigrahy at Harvard Medical School and Hammock, announced the findings in&nbsp;<a href="https://doi.org/10.1073/pnas.2107771118"><em>Proceedings of the National Academy of Sciences</em>&nbsp;(PNAS)</a>&nbsp;this week.</p> September 28, 2021 - 10:54am Andy Fell /blog/anti-inflammation-drug-combination-may-help-pancreatic-and-liver-cancer-patients Researchers Identify a Potentially Safer Approach to Opioid Drug Development /blog/researchers-identify-potentially-safer-approach-opioid-drug-development <p>Opioids are powerful painkillers but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death. A recent study from researchers at the ºÙºÙÊÓƵ Center for Neuroscience contradicts existing thinking about how opioid drugs cause tolerance and respiratory depression, and suggests a new, balanced approach to developing safer analgesics. The work was published July 13 in&nbsp;<em>Neuropsychopharmacology</em>.</p> August 24, 2021 - 8:01am Andy Fell /blog/researchers-identify-potentially-safer-approach-opioid-drug-development Turning Tarantula Venom Into Pain Relief /news/turning-tarantula-venom-pain-relief <p>Researchers at ºÙºÙÊÓƵ are developing a new type of pain medication from an unusual source — tarantula venom.</p> <p>The project is part of the&nbsp;<a href="https://heal.nih.gov/">NIH Helping to End Addiction Long-Term (HEAL) Initiative</a>, aimed at ending opioid addiction and creating non-addictive therapies to treat pain.</p> July 14, 2021 - 12:07pm Andy Fell /news/turning-tarantula-venom-pain-relief Popular Painkiller Ibuprofen Affects Liver Enzymes in Mice /news/popular-painkiller-ibuprofen-affects-liver-enzymes-mice <p>The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis. The study in laboratory mice also shows marked differences between males and females.&nbsp;</p> <p>The work is published Feb. 25 in&nbsp;<a href="https://rdcu.be/b2ME1">Scientific Reports</a>.</p> March 11, 2020 - 10:57am Andy Fell /news/popular-painkiller-ibuprofen-affects-liver-enzymes-mice Psychedelic Drugs Change Structure of Neurons /news/psychedelic-drugs-change-structure-neurons <p>A team of scientists at the University of California, Davis, is exploring how hallucinogenic drugs impact the structure and function of neurons — research that could lead to new treatments for depression, anxiety&nbsp;and related disorders.</p> June 12, 2018 - 6:58am Andy Fell /news/psychedelic-drugs-change-structure-neurons Scorpion Venom Yields Clues for Developing Better Pharmaceuticals /news/scorpion-venom-release <p>When a chemical found in the venom of one species of scorpion permeates cells, it loses its toxic potency, suggesting it may be a useful tool in developing new therapeutic medicines.&nbsp;&nbsp;</p> April 15, 2016 - 2:15pm Patricia Bailey /news/scorpion-venom-release