Chemistry Content

�ٺ��Ƶ Researchers Achieve Total Synthesis of Ibogaine

Andy Fell — February 06, 2025 - 10:45am

Ibogaine — a psychoactive plant derivative — has attracted attention for its anti-addictive and anti-depressant properties. But ibogaine is a finite resource, extracted from plants native to Africa like the iboga shrub (Tabernanthe iboga) and the small-fruited voacanga tree (Voacanga africana). Further, its use can lead to irregular heartbeats, introducing safety risks and an overall need to better understand how its molecular structure leads to its biological effects.

Developing Molecular Windows to Advance Health

Andy Fell — January 16, 2025 - 4:50pm

The image is like an abstract stained-glass window. Set against a black background, a nexus of fluorescent greens, yellows and blues mushrooms out into purples and deep reds. It’s striking — the beauty of cells when viewed through the lens of mass spectrometry.

Anti-Anxiety and Hallucination-Like Effects of Psychedelics Mediated by Distinct Neural Circuits

Andy Fell — November 14, 2024 - 10:06am

New research suggests that it could be possible to separate treatment from hallucinations when developing new drugs based on psychedelics. The anti-anxiety andhallucination-inducing qualities of psychedelic drugs work through different neural circuits, according to research using a mouse model. The work is published Nov. 15 in Science.

Exploring the Psychedelics Within Us

Andy Fell — October 21, 2024 - 3:00pm

Our bodies are pharmaceutical factories. From the hormones that regulate our blood sugar to the neurotransmitters that act as the body’s natural painkillers, these endogenous — produced within the body — chemicals ensure our functionality and survival.

But did you know that our bodies also naturally produce psychedelics?

In the 1950s, researchers found chemical signatures of N,N-dimethyltryptamine (DMT) in mammalian bodies, including in humans.

Researchers Step Closer to Mimicking Nature’s Mastery of Chemistry

Andy Fell — January 10, 2024 - 8:45am

In nature, organic molecules are either left- or right-handed, but synthesizing molecules with a specific “handedness” in a lab is hard to do. Make a drug or enzyme with the wrong “handedness,” and it just won’t work. Now chemists at the University of California, Davis, are getting closer to mimicking nature’s chemical efficiency through computational modeling and physical experimentation.

�ٺ��Ƶ, Mars Researchers Discover Scalable Production Technique for Low-Calorie Sugar Substitute

Andy Fell — October 24, 2023 - 9:30am

Scientists at the University of California, Davis, in partnership with the Mars Advanced Research Institute, have announced a significant breakthrough in the production of low-calorie sugar substitutes, such as allulose. This discovery could help address one of the primary obstacles to the widespread adoption of these alternatives: production costs.

The Dark Matter of Food: Uncovering the Structures of Carbohydrates

Andy Fell — May 16, 2023 - 1:56pm

We’ve all heard the advice: “Eat more fiber.”

But the reality behind that seemingly simple recommendation is much more complex when it comes to human health. While consumption of dietary fiber has been associated with decreased risks of obesity, type 2 diabetes, coronary heart disease and certain gastrointestinal disorders, honing in on how specific fibers — or more broadly, carbohydrates — from different foods affect the gut microbiome and thus human health remains a black box.

Receptor Location Matters for Psychedelic Drug Effects

Andy Fell — February 16, 2023 - 11:00am

A new study reveals receptor location impacts psychedelic drug effects. Learn how �ٺ��Ƶ researchers are exploring implications for mental health treatment.

How to Make Chemistry a Gateway — Not a Gatekeeper — to STEM?

Karen Michele Nikos — June 08, 2022 - 5:10pm

A chemistry course bolsters both academic and social-emotional learning.

EPA Presents Green Chemistry Challenge Award to Chemistry Professor

Andy Fell — June 07, 2022 - 3:00pm

The U.S. Environmental Protection Agency has awarded one of five Green Chemistry Challenge Awards to Mark Mascal, professor of chemistry at the University of California, Davis, together with Origin Materials Inc. and its co-CEO John Bissel.